DNA Base Pairing
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Order NowIn every base pairing, a Purine always pairs with a Pyrimidine. In DNA replication, the DNA strands pair with its complementary base. A purine pairs with a Pyrimidine.
The Purines are: Adenine (A) and Guanine (G). Â they have a larger molecular structure than pyrimidines.
The pyrimidines are Cytosine (C) and Thymine (T). their molecular structure is smaller when compared with the Purines.
In essence, a large molecule pairs with a small molecule (Purine-Pyrimidine or Pyrimidine-Purine). Â The Purine-Purine or Pyrimidine-Pyrimidine bond does not form because it would anot fit into the double-helix structure of a DNA. This is called Watson-Crick pairing.
 A always pairs with T and C with G
Each bas pair is tightly bound to one another by Hydrogen bonds. This is a very strong type of bond.
A – Adenine
C – Cytosine
T – Thymine
G – Guanine
REFERENCES.
http://wps.prenhall.com/esm_krogh_biology_3/17/4438/1136322.cw/index.html
http://wps.prenhall.com/esm_krogh_biology_3/17/4439/1136522.cw/index.html
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/B/BasePairing.html